Tópicos destacados sobre tuberculosis del Congreso de la Asociación Latinoamericana de Tórax: ALAT 2025

Abstract

This article summarizes some of the most relevant approaches to tuberculosis (TB) presented at tje congress of the ALAT (Latin American Thoracic Association) 2025, which may be summarized in the following ; a) The need to identify the groups most vulnerable to the disease, all of whom should be treated if latent TB is demonstrated; b) the high mortality of Central Nervous System tuberculosis, which is why it is important to establish prolonged treatment with drugs that better penetrate the brain and meninges, along with treating the associated inflammation; c) the higher incidence of TB in pregnant women, especially in the postpartum period, TB under these conditions can be treated with standard regimens, except if there is resistance to these drugs. Some anti-TB drugs should also be considered harmful to the fetus, d) the potential capacity of TB to induce genomic changes that may culminate in the appearance of a neoplasm; e) the need for people living with HIV to identify and treat latent or active TB early, due to the high lethality of co-infection; f) TB risk in patients with diabetes mellitus with poor metabolic control who also have a slower cure and more adverse reactions to TB therapy.